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Benign prostatic hyperplasia (BPH) is the non-malignant growth of the prostate gland that strictly develops as an age-related condition, starting by 40 years of age and impacting up to 60% of men in their 60s and 80% of men in their 80s.1,2 BPH can further lead to the clinical complication of lower urinary tract symptoms (LUTS)—the prevalence of which increases with advancing age—and up to 41% of men report bothersome LUTS over the age of 40.1,3,4 However, not all men with histologic BPH develop significant LUTS, and at times, men without histologic BPH can develop LUTS.1 Another clinical complication surrounding LUTS and BPH is that the prostate tends to increase in size in aging men, termed benign prostatic enlargement (BPE).1 However, again, not all men with LUTS will have concomitant BPE, and not all men with BPE will have bothersome LUTS.1 In fact, many men with significant LUTS and bother have a normal-sized prostate, and many men with large prostates present with only a few symptoms, if any.1 Hence, BPH might overlap with LUTS and BPE in some patients but is not always typically the causal factor for these conditions in every patient. Recently, an association has been reported between erectile dysfunction (ED) and LUTS, with voiding, nocturia, and quality of life (QoL) impairment due to LUTS being reported as independent risk factors for ED.3 ED has significant implications on the QoL and psychosocial health of men and their partners.5 The most common and well-known risk factor for ED is aging, whereby men as young as 40 can have a 40% chance of developing some form of ED, which increases by about 10% every decade thereafter.5,6 Apart from these, overactive bladder (OAB) is another common bladder complication whose prevalence increases with age.7 The storage symptoms of LUTS are synonymous with OAB, including urgency (usually with nocturia) and frequency (with or without urgency incontinence) that impacts overall QoL, sexual function, sleep, and mental health.8,9 Conclusion Aging is the most well-known risk factor for BPH, LUTS, OAB, and ED; however, BPH does not necessarily lead to BPE and LUTS.1,2,7 Apart from aging, LUTS is also a significant risk factor for ED.3 Recognizing these nuances can help guide more personalized and effective management strategies. |
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Alfoo- Relief from LUTS-BPH
ALFOO, containing Alfuzosin molecule, is Anti-BPH which helps in treatment of LUTS due to BPH in Young Sexually Active Male in 40-60 year old age group
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