L-Carnitine and Coenzyme Q10 Show Promise in Managing BPH-Related Prostate Volume and Erectile Function

A recent randomized controlled trial suggests that L-carnitine (LC) and Coenzyme Q10 (CoQ10) supplementation, when combined with finasteride, may enhance prostate health and erectile function in men with benign prostatic hyperplasia (BPH).

The study involved 50 male participants with BPH, randomly divided into two groups:

• one receiving finasteride alongside LC and CoQ10 supplements

• other receiving finasteride with a placebo

Over the eight-week trial period, outcomes included:

• International Prostate Symptom Score (IPSS)

• International Index of Erectile Function (IIEF)

• Quality of life (QoL) scores

• Prostate-specific antigen (PSA) levels

• Prostate volume assessed via ultrasound

Results showed a significant reduction in prostate volume (p < 0.001) and a marked improvement in erectile function (p < 0.001) in the supplement group compared to the control group. However, no significant differences were observed between groups for IPSS, QoL scores, or PSA levels.

These findings suggest that LC and CoQ10 supplementation may provide additional benefits in reducing prostate volume and improving erectile function without affecting urinary symptoms or quality of life measures. The study highlights the potential for incorporating these supplements into standard BPH therapies to enhance patient outcomes. Further research is needed to explore their long-term effects and broader clinical applications.