Elobixibat reduces bile acid reabsorption in the ileum, increasing their concentration in the colon to enhance motility and secretion.¹

Fast Relief:³

• Median time to first SBM 5 hrs
• 86% patients had first SBM within 24 hrs
• SBM improved to 6.4 SBMs/week by week 1 from baseline

Long Term Sustained Efficacy:³

• Relief is sustained for 12 months with maintenance dose

Locally Acting & Safe for Long-Term Use:³

• 1 year study with 340 patients
• No Drug Resistance
• Induces no electrolyte imbalance

Proven Safety in Elderly & Diabetic Patients ^4,5

• Study with 1049 Patients
• Improves rectal sensory thresholds: Reduces defecatory desire volume by 9 mL
• Low risk of drug-drug interaction

Cardiac & Renal Safety ^6,7

• Reduces straining
• Prevents changes in BP between before & after defecation
• >99.99% elimination is through feces with negligible renal route elimination