Probiotic Mixture Reduces Allergic Rhinitis Symptoms in Children, Study Finds

A randomized controlled trial has shown that a probiotic combination of Bifidobacterium longum and Lactobacillus plantarum (NVP-1703) significantly alleviates symptoms of allergic rhinitis (AR) in children. 
The study included children aged 6 to 19 with perennial AR, who were treated with NVP-1703 or a placebo over a 4-week period.
Results indicated that the total nasal symptom score (TNSS) in the NVP-1703 group decreased significantly compared to the placebo group. Symptom relief was observed both in the morning and evening, with notable improvements in nasal symptom duration and quality of life (QoL), particularly in reducing mouth breathing and itchy nose.
 Additionally, the NVP-1703 group showed reduced levels of inflammatory markers, specifically lower ratios of interleukin (IL)-4 and IL-5 to IL-22, which are associated with allergic responses.
No adverse events were reported, confirming the safety of NVP-1703 in children. These findings suggest that probiotics could offer a safe and effective treatment for managing AR in children, potentially improving both symptom control and overall quality of life. The study adds to the growing body of evidence supporting the role of probiotics in treating allergic conditions.