Resurgence of Sulfonylureas

With the recent CAROLINA trial debunking the CV safety concerns of SUs, there is a renewed interest in the role of SUs in T2DM management especially considering their superior efficacy over other drugs classes

Multiple drugs have been discovered for the management of T2DMover the last few years. Still, the role of sulfonylureas in T2DM management is undisputable. With the recent CAROLINA trial debunking the CV safety concerns of SUs, there is a renewed interest in the role of SUs in T2DM management especially considering their superior efficacy over other drugs classes and advantages of modern sSUs like Gliclazide MR.