Efficacy of a universal dentin adhesive containing mesoporous bioactive glass in alleviating dentin hypersensitivity

According to a recent study, the universal adhesive with mesoporous bioactive glass (MBG) provided relief from dentin hypersensitivity, with effectiveness that is identical with or even superior to that of specific desensitizing agents. It can be utilized as an efficient in-office treatment for dentin hypersensitivity relief. This study’s findings were published in the journal, Scientific Reports.

This randomized study included 225 teeth from 39 patients to evaluate the effectiveness of a desensitizing agent with oxalate/resin polymer and a universal adhesive containing MBG for relieving dentin hypersensitivity. The assessment of efficacy was done using Schiff sensitivity score (SSS) and visual analog scale (VAS). The teeth with dentin hypersensitivity in split quadrants were treated with either MS Coat ONE or Hi-Bond Universal with MBG as the functional additive. Standardized stimulus protocols including air, cold, and acid were used for assessments at baseline, immediately after application, and at 1- and 2-week follow-ups. The primary outcome of the study was the SSS difference, whereas the VAS difference was the secondary outcome.

An instant decrease in DH was observed following exposure to air stimuli, showing a significant reduction in Group HB compared to Group MS (p = 0.017). The reduction in response to cold stimuli showed a gradual cumulative effect, consistently resulting in larger reductions in Group HB than in Group MS (p ≤ 0.037). Both groups effectively handled acidic stimuli, with no significant variances (p > 0.05). The VAS scores gradually decreased throughout the follow-up duration (p < 0.0001).

The above study showed that dentin hypersensitivity was successfully relieved by the mesoporous bioactive glass containing universal adhesive.