The effect of various desensitizers on pulpal blood flow after full crown preparation using laser Doppler flowmetry

In a recent study, similar levels of effectiveness were observed in treating dentine hypersensitivity and pulpal blood flow with Bifluoride 12, Teethmate, and Copal Varnish. This study’s findings were published in the journal Odontology.
18 patients with a total of 42 teeth suffering from dentine hypersensitivity after full crown preparations were randomly divided to receive treatment with Bifluoride 12, Teethmate, or Copal Varnish. The severity of dentine hypersensitivity was assessed using a Schiff air index (SAI) and visual analog scale (VAS). The assessment of pulpal blood flow involved the use of laser Doppler flowmetry (LDF), with the findings recorded in perfusion units (PU). Evaluations were conducted at the initial stage, after five minutes, after seven days, and after one month subsequent to the administration of desensitizing agents. Statistical analysis was carried out using Wilcoxon and two-way ANOVA tests (p value < 0.05).

The tested desensitizers did not show any significant difference in terms of VAS and PU values. VAS values significantly decreased at seven days and one month after the desensitizers were applied, compared to the baseline in all groups. Only the Copal Varnish group exhibited a notable difference in PU values at the five-minute and seven-day intervals post-desensitizer application (p value < 0.05). A statistically significant difference was found between different time points in relation to SAI scores in all groups (p value < 0.05).

Thus, it can be concluded that Bifluoride 12, Teethmate, and Copal Varnish demonstrated similar effectiveness in managing dentine hypersensitivity and pulpal blood flow. To fully evaluate their impact on pulpal status, it is important to conduct long-term clinical trials with larger sample sizes and histological studies.