According to a recent study, Silver diamine fluoride (SDF) and Nano Silver Fluoride (NSF) after 6 months exhibited significant enhancements in children's Oral Health-Related Quality of Life (OHRQoL). It was observed that NSF had a significantly superior impact on OHRQoL compared to SDF. This study’s results were published in the Journal of dentistry.

This study involved 360 children under the age of 4, each having at least one active lesion with an International Caries Detection and Assessment System (ICDAS) score of ≥3. They were randomly divided into two groups: one receiving NSF at the beginning, and the other receiving SDF at the start and after 6 months. The Oral Health-Related Quality of Life (OHRQoL) was assessed using the Arabic version of the Early Childhood Oral Health Impact Scale (A-ECOHIS). Additionally, group comparisons were made using the chi-square test, and the impact of the intervention on OHRQoL was analyzed through multiple linear regression.

In the bivariate analysis and regression analysis (B= -5.02) with confounder adjustments, it was observed that NSF exhibited significantly lower A-ECOHIS scores compared to SDF after a period of 6 months. Both groups showed significant decreases in the A-ECOHIS domain and total scores, except for the social interaction domain in the SDF group.

The above study demonstrated that after a 6-month period, both NSF and SDF led to a significant improvement in children's OHRQoL. However, NSF had a notably greater impact on OHRQoL compared to SDF.

According to a recent study, the bioactive glass-ceramic (HX-BGC) and NovaMin toothpaste exhibited more significant effects in addressing dentinal hypersensitivity when compared to the negative control group. No adverse reactions associated with the experimental toothpastes were noted. This study’s research findings were published in the Journal of Dentistry.

In this single-center, randomized, double-blind study, participants were randomly allocated to use one of the HX-BGC, NovaMin, or negative control toothpastes. Follow-up examinations were conducted immediately after a single use and at 2 weeks, 4 weeks , and 6 weeks. Schiff and Yeaple indices were used for intra-group and inter-group comparisons. The safety of the experimental toothpastes was evaluated through participant feedback and oral soft tissue examinations.

There was an increase in Yeaple indices across all groups, with significant differences noted between the HX-BGC group and the other two groups after a continuous 2-week period of use. Schiff indices decreased in all groups, with the NovaMin group demonstrating significant differences when compared to the negative control group. Significant improvement was observed in both the HX-BGC group and the NovaMin group by weeks 4 and 6 compared to the negative control group in both indices. The HX-BGC group exhibited better results in the Yeaple index compared to the NovaMin group. Additionally, no serious adverse reactions related to the toothpastes were reported or observed among the participants.

The above study confirmed the efficacy of HX-BGC in treating dentinal hypersensitivity and supported the clinical use of dentifrices formulated with HX-BGC. Both the HX-BGC and NovaMin toothpaste groups exhibited significantly greater efficacy in managing dentinal hypersensitivity compared to the negative control group. There were no adverse reactions reported in relation to the experimental toothpastes.

According to a recent study, the utilization of 5% glutamine for oral care has been linked to a decreased occurrence of oral disorders and pneumonia, as well as a notable decrease in oral flora following neurosurgery. This study’s results were published in the journal, Medical science monitor.

In this parallel, double-blind, randomized trial, three hundred patients meeting the inclusion criteria were randomly allocated into three groups. The control group (n=100) received routine oral care with saline, the experimental group (n=100) received oral care with 5% glutamine, and a compound chlorhexidine group (n=100) was used as a positive control. Data on dryness, local debris, halitosis, oral mucositis disorders, oral mucositis, and oral flora types were collected  and determined within all groups.

At the end of the study, the glutamine oral care group exhibited a significant decrease in the incidence of local debris, halitosis, oral mucositis,  dryness, and other oral mucositis disorders when compared to the control group. Additionally, there was a notable reduction in oral flora types in both the glutamine and chlorhexidine groups.

The above study demonstrated that the use of 5% glutamine in oral care is associated with a lower occurrence of oral disorders and pneumonia, as well as a significant reduction in oral flora after undergoing neurosurgery.

According to a recent study, the desensitizing paste with 8% L-arginine, calcium carbonate, and potassium nitrate effectively blocked dentinal tubules and minimized dentin permeability. It alleviated both immediate and prolonged dentin hypersensitivity to different stimuli, demonstrating its potential role in the treatment of dentin hypersensitivity. This study's findings were published in the journal, BMC oral health.

The dentin surfaces of 24 third molars, each with a thickness of 2 mm were divided into two groups of 12. The experimental paste was given to one group, whereas the other group received a placebo devoid of a desensitizer. Scanning electron microscopy (SEM) and dentin permeability measurement were used to assess the permeability and sealing ability. The effects of the pastes on hypersensitivity were examined in a triple-blind, randomized clinical trial involving 16 eligible patients. Patients responsiveness to touch, cold, and spontaneous stimuli was measured at different time points following treatment using the VAS scale. Statistical examinations, such as Shapiro-Wilk, Friedman, Mann-Whitney U, and Wilcoxon tests, were conducted to evaluate the data.

In the permeability test, the experimental group demonstrated a significant decrease in dentin permeability (P = 0.002) compared to the control group (P = 0.178). Examination of SEM images revealed that most dentinal tubules in the intervention samples were occluded. Clinically, both groups experienced a notable reduction in all three types of sensitivity evaluated throughout the study. However, there was no significant differences in sensitivities between the two groups, except for cold sensitivity at three months post-treatment (P = 0.054).

The above study demonstrated that by using a desensitizing paste composed of 8% L-arginine, calcium carbonate, and potassium nitrate, the dentinal tubules were effectively blocked and dentin permeability was minimized. It successfully relieved both immediate and long-lasting dentin hypersensitivity caused by various stimuli, showcasing its promising application in the treatment of dentin hypersensitivity.

According to a recent study, soaking dentures in 1% sodium hypochlorite for 10 minutes without any brushing was found to be a simple, quick, affordable, and efficient way to clean the dentures of hospitalized patients. This study’s results were published in the Journal of applied oral science.

The maxillary complete dentures of 340 hospitalized participants were subjected to random cleaning using 17 different protocols (n=20 participants). The cleaning methods included brushing with distilled water, neutral liquid soap, or toothpaste, (considered as controls), as well as immersion in chemical solutions such as 1% sodium hypochlorite, alkaline peroxide, 0.12% or 2% chlorhexidine digluconate. Additionally, some dentures were subjected to microwave irradiation (650 W for 3 min), either alone or in combination with brushing. The effectiveness of these protocols was assessed by evaluating the biofilm of the intaglio surface of the maxillary complete dentures before and after cleaning. Two methods used for evaluation include : microbiological quantitative cultures on blood agar and Sabouraud Dextrose Agar (CFU/mL) as well as denture biofilm coverage area (%). The collected data were analyzed using the Wilcoxon and Kruskal-Wallis tests.

Significant reductions in the percentage area of denture biofilm and microbial and fungal load were achieved by all 17 protocols. The most significant reductions in denture biofilm area were observed with 1% hypochlorite solution with or without brushing, and with 2% chlorhexidine solution and microwave irradiation combined with brushing. The greatest reductions in microbial and fungal load were noted in groups that used 1% hypochlorite solutions and 2% chlorhexidine, as well as microwave irradiation, regardless of brushing .

Thus, it can be concluded that a single immersion of dentures in 1% sodium hypochlorite for 10 minutes, without brushing is a simple, quick, cost-effective, and efficient method for cleaning dentures in hospitalized patients.