Dentinal Hypersensitivity
Dentinal Hypersensitivity is a chronic condition with acute episodes. When dentine is exposed, which usually happens due to gingival recession & enamel damage (erosion, abrasion, attrition, and abfraction), external triggers (such as a cold drink) can stimulate the nerves inside the tooth, causing the characteristic short, sharp sensation of tooth sensitivity.1
The most common trigger for realizing sensitivity is cold.
1. Dababneh RH, Khouri AT, Addy M. Dentine hypersensitivity an enigma? A review of terminology, mechanisms, aetiology and management. Br Dent J.1999;187:606–611
What is Calcium Sodium Phosphosilicate?
CSPS is a particulate, bioactive glass material that degrades in the aqueous oral environment to release calcium and phosphate ions, leading to formation of Hydroxycarbonate Apatite on the dentine surface. This process creates a physical barrier that mitigates the impact of external stimuli on fluid movement within dentinal tubules.1
1. S. Schlafer et al. Journal of Dentistry 91S (2019) 100003.
Why Vantej?
- CSPS as the major ingredient
- Extra foaming & Mint flavor
- Extensively studied molecule
1. Xiong Zheng-hui, et al. Occluding eects of three new calcium desensitizers on dentinal tubules in vitro. Zhongua Kou Qiang Yi Xue Za Zhi. 2011 Apr;46(4):214-7.
Where to Use?
In Dentinal Hypersensitivity
- Dentinal Hypersensitivity is a chronic condition with an acute episodes, usually stimulated by external triggers – mainly a cold beverage.1
- Drinking or eating something cold/freezing is the most common sensation to realize Dentinal Hypersensitivity.2,3
1. Dababneh RH, Khouri AT, Addy M. Dentine hypersensitivity — an enigma? A review of terminology, mechanisms, aetiology and management. Br Dent J.1999;187:606–611.
2. Hydrodynamic Theory Kramer IRH. The relationship between dentine sensitivity and movements in the contents of dentinal tubules. Br Dent J. 1955;98:391–392.
3. Brännström M. The elicitation of pain in human dentine and pulp by chemical stimuli. Arch Oral Biol. 1962;7:59–62
How to Use?
- Squeeze some toothpaste about half the length of the bristle head and brush for 1-2 minutes using a gentle, vertical sweeping motion away from gums.
- Spit out the paste and rinse with water, do not swallow.
- Avoid eating or drinking anything within half an hour of brushing.
- Brush twice daily for best results.
Continued long-term release of Ca and P to build enamel layer
- Vantej, when comes into contact with saliva, water releases particles of calcium and phosphorus ions, protected by the glass particles.
- Saliva gets saturated with the ions needed for remineralization.1
- Demineralized lesions attract Ca & P ions.1
- Building new hydroxy appetite crystals to remineralise the defect from roots to the top.
1. Anora B, et al. NovaMin and Dentin Hypersensitivity – In Vitro Evidence of Ecacy. J Clin Dent 2010
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IBS patients need more than just medication; they require guidance to understand and improve their gut health. DailyBloom’s tailored IBS plan works hand-in-hand with doctors' medical management, offering personalized weekly care.Introducing DailyBloom, India's First Integrated IBS Care Solution
Air quality and Upper Respiratory Tract Infections (URTIs)
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Air pollution and URTIs are interconnected global health issues. Pollutants like PM, pollen, and harmful gases contribute to allergic diseases and worsen conditions. URTIs, often viral, are challenging to manage due to overlapping symptoms and antibiotic misuse.Air quality and Upper Respiratory Tract Infections (URTIs)
Managing Allergic Rhinitis
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AR symptoms worsen at night, leading to poor sleep and impaired QoL. Nighttime dosing of antiallergic agents can control this. Nasal congestion, inflammation, and airway resistance from AR disrupt sleep and are major contributors to impaired QoL.Managing Allergic Rhinitis
Unraveling the Clinical Traits of Refractory GERD and Their Prevalence in Indian Population
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Act Now: Addressing PPI-Refractory GERDBixibat- the Only Elobixibat Brand in India
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Elobixibat works locally in the GI tract, making it suitable for long-term use of up to one year. Proven safe for elderly, renal, cardiac, and diabetic patients, Elobixibat ensures broad patient compatibility without compromising safety.Bixibat- the Only Elobixibat Brand in India
Dual action of Pro-mobility and Pro-Secretory with Elobixibat
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Elobixibat reduces bile acid reabsorption in the ileum, increasing bile acid concentration in the colon to stimulate motility and secretion. 86% of patients experienced their first spontaneous bowel movement (SBM) within 24 hours.Dual action of Pro-mobility and Pro-Secretory with Elobixibat
Detecting and Handling Refractory GERD: The Schemas at Work
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Elobixibat is now in India
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Chronic constipation impacts 12-17% of Indian adults, surpassing the global average of 10%. Elobixibat, a minimally absorbed partial IBAT inhibitor, offers a dual action that promotes colonic motility and secretion.Elobixibat is now in India
GERD Management: Overcoming the Hurdles of PPI Treatment
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Deciphering the Prevalence and Clinical Traits of FED in Patients With PPI-Unresponsive Reflux Symptoms
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clone of Breakthrough drug from Dr.Reddy's with dual action pf Pro-motility & Pro-Secretory action that combats chronic constipation
clone of Breakthrough drug from Dr.Reddy's with dual action pf Pro-motility & Pro-Secretory action that combats chronic constipation
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The Interconnection Between Air Pollutants and URTIs
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Minimize Adverse Events, Maximize Adherence With PEG!
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Act Now: Reduce Adverse Events with PEG!Role of Bixibat in Chronic Constipation Management
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Role of Bixibat in Chronic Constipation ManagementBreakthrough drug from Dr.Reddy's with dual action of Pro-motility & Pro-Secretory action that combats chronic constipation
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Pop & Go: The Fast Track to Oral Drug Delivery with Dissolving Tablets
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Clinical Guidance for Optimal Endodontic Management of Traumatized Permanent Teeth
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Odontalgia Odyssey Navigating Dental Pain Management in India
Odontalgia Odyssey Navigating Dental Pain Management in India
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Challenges and Insights: Understanding the Raise of Dental Caries in India
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Recommendations by American Dental Association (ADA) for Dental Pain Management
Recommendations by American Dental Association (ADA) for Dental Pain Management
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Healing or Hurdling? Tracking Adherence to Post-Extraction Guidelines After Surgery
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Endodontic Pain Relief: Navigating the Behavioural, Pharmacological, and Anaesthetic Triad
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Emerging Paradigms in Dentistry: Synergies of AI and Nanotechnology in Caries Management
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Essential Potty Chart Guide For Parents!
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Guide to parents getting ready for potty trainingEmpower Parents: Simple Guide To Potty Training
Empower Parents: Simple Guide To Potty Training
Potty training, Do's and Dont's for Every parentCritical Bowel Health Insights For Parents
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Join Forces With Parents: Potty Training Success!
Join Forces With Parents: Potty Training Success!
Empower Parents with These Expert Potty Training Tips!Join Forces With Parents: Potty Training Success!
Priority: Impact of rHuEPO on CKD Anemia Care
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Priority: Impact of rHuEPO on CKD Anemia CareMaster Hb Goals: The Winning Score for Haemodialysis Success!
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The score that leads towards victory in haemodialysis management.Hb levels are a critical score for haemodialysis patientsMaster Hb Goals: The Winning Score for Haemodialysis Success!
Transform Dialysis: Tailored Care or One Approach?
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Hb targets for patients with CKD receiving ESA therapy can vary between predialysis and dialysis patientsTransform Dialysis: Tailored Care or One Approach?
Revamp CKD Anemia Care: A Tailored Approach
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Anemia in chronic kidney disease treatment standard and personalizationSevere Anemia: A Hidden Threat in CKD
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Renal Anemia Solutions — Today's Advancements
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Current status of renal anemia pharmacotherapyDialysis Breakthroughs: What’s New?
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Unveiling developments in dialysis therapyTransform Surgery Now with AI Visual Guidance
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AI-driven 3D anatomical reconstruction enhances surgical planning and intraoperative navigation. Computer vision interprets images, aiding precise demarcation of surgical sites.Transform Surgery Now with AI Visual Guidance
Why Digital Healthcare Marketing is Essential? Learn from Our Expert Digital Marketers!
Why Digital Healthcare Marketing is Essential? Learn from Our Expert Digital Marketers!
In today’s digital world, 90% of patients choose their doctors based on online reviews. Digital marketing empowers healthcare providers to educate patients, enhance visibility, and attract proactive behaviors.Why Digital Healthcare Marketing is Essential? Learn from Our Expert Digital Marketers!
Transform Your Healthcare Practice with a Strong Online Presence
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Gastric Acid Suppression and The Unmet Needs of PPIs
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Pin down the unmet needs of proton pump inhibitors in gastric acid suppression. Explore the clinical impact of PPI drawbacks.Gastric Acid Suppression and The Unmet Needs of PPIs
HoLEP: Boosting BPH Treatment Success!
HoLEP: Boosting BPH Treatment Success!
Worthy choice for higher efficacy and safety in BPH Treatment.oRAKT: Surgical Insights Unveiled
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Orthotopic Robot-Assisted Kidney Transplant.The Clinical safety of Vonoprazan in the Gastric Acid Management
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The Clinical Effectiveness of Vonoprazan for Gastric Acid complications
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Recognizing the clinical benefits of vonoprazan over proton pump inhibitors. Find out how vonoprazan is superior to proton pump inhibitors in gastric acid management.The Clinical Effectiveness of Vonoprazan for Gastric Acid complications
Discerning the MOA of Vonoprazan in Gastric Acid Management
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Identifying the mode of action of vonoprazan for digestive acid control. Explore the clinical intricacies of vonoprazan in managing gastric acid.Discerning the MOA of Vonoprazan in Gastric Acid Management
Unlocking Hidden Struggles: Neurogenic LUT Dysfunction
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Neuro urological disorders present a multifaceted pathology.Unlocking Hidden Struggles: Neurogenic LUT Dysfunction
Pediatric Cough Management: A Comprehensive Yardstick
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Chronic cough in children, lasting over four weeks, critically impacts quality of life and demands precise diagnosis and treatment. Despite targeted therapies, gaps remain, especially for acute viral cases. Urgent research and tailored guidelines are essential to advance care and improve outcomes.Pediatric Cough Management: A Comprehensive Yardstick
Diagnosis and Management of Chronic Cough in Pediatric Patients
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This article provides expert guidelines for managing chronic cough in children under 14, emphasizing a pediatric-focused approach. It outlines essential diagnostic steps, such as chest radiographs and spirometry, and highlights the need for personalized care and TB screening in high-risk areas.Diagnosis and Management of Chronic Cough in Pediatric Patients
X-ray patterns and insights for different cough categories
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Analyzing X-rays across various categories of cough patients, such as smokers' cough, bronchospastic cough (Asthma), infectious cough (Pneumonia), and postnasal drip cough—offers valuable insights into each condition.X-ray patterns and insights for different cough categories
The impact of long-lasting coughs on diverse patient population
The impact of long-lasting coughs on diverse patient population
Chronic coughs worsen health for those with diabetes, GERD, asthma, COPD, heart issues, allergies, & the elderly. They disrupt blood sugar, increase reflux, trigger asthma attacks, obstruct breathing, stress the heart, & heighten allergy sensitivity.The impact of long-lasting coughs on diverse patient population
Impact of untreated long-lasting cough in patients
Impact of untreated long-lasting cough in patients
Chronic cough affects more women than men and can lead to fatigue, sleep disturbances, musculoskeletal pain & psychological issues like anxiety. It may worsen asthma or GERD. Severe coughing episodes can cause rib fractures and urinary incontinence.Impact of untreated long-lasting cough in patients
Decode the 8 week long lasting cough!
Decode the 8 week long lasting cough!
Identifying patients with chronic cough involves assessing symptoms, past infections, smoking history, medication use, and environmental exposure. Common red flags include coughing up blood, shortness of breath, and conditions like asthma or GERD.Decode the 8 week long lasting cough!
Ozone Therapy and pH-Sensitive Nanocarriers in Modern Dentistry
Ozone Therapy and pH-Sensitive Nanocarriers in Modern Dentistry
Discover transformative dental innovations: Ozone therapy offers pain-free caries treatment by eliminating bacteria and aiding remineralization. pH-responsive nanocarriers ensure precise drug delivery, enhancing outcomes and patient comfort. Embrace the future of dentistry with this read!Ozone Therapy and pH-Sensitive Nanocarriers in Modern Dentistry
Modern Restorative Dentistry
Modern Restorative Dentistry
Revolutionize restorative dentistry with advanced nanocomposites and smart technology. This article explores innovations that deliver superior strength, minimal shrinkage, and adaptive properties, enhancing both durability and oral health with precision.Modern Restorative Dentistry
Nanotechnology advancements in dental therapeutics
Nanotechnology advancements in dental therapeutics
Dive into the future of dental care with nanotechnology! This article explores how organic liposomes and hydrogels, along with silver and zinc nanoparticles, provide targeted, precise treatments to fortify enamel and combat decay, revolutionizing caries prevention and tooth repair.Nanotechnology advancements in dental therapeutics
Advancing Regenerative Dentistry
Advancing Regenerative Dentistry
Explore the forefront of dentistry with advancements in regenerative medicine and AI. Delve into the transformative impact of stem cell technologies, 3D bioprinting, and AI-enhanced diagnostics and prosthetic design, driving precision and innovation in dental care.Advancing Regenerative Dentistry
Potty Training Pitfalls: What to Avoid
Potty Training Pitfalls: What to Avoid
What to avoid while potty training your kidsSuccessful Toilet Training: A Step-by-Step Guide
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Step-by-step guide for toilet trainingPEG 3350 Offers an Edge Over Lactulose in The Management of Functional Constipation
PEG 3350 Offers an Edge Over Lactulose in The Management of Functional Constipation
PEG 3350 Offers an Edge Over Lactulose in The Management of Functional ConstipationPEG 3350 Offers an Edge Over Lactulose in The Management of Functional Constipation
Inadequate Constipation Treatment Turns Simple Discomfort Into A Daily Battle
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Effects of inadequate treatment of functional constipationInadequate Constipation Treatment Turns Simple Discomfort Into A Daily Battle
Unlocking the Path to Pediatric Constipation Relief: Guideline-Backed Insights
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Complete and Long Lasting Symptomatic Relief of Functional Constipation Is the Need of the Hour
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PEG 3350 Long-term Therapy:To Achieve Functional Constipation Treatment Goals
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Darbepoetin Alfa: Convenient Solution For Managing Anemia!
Darbepoetin Alfa: Convenient Solution For Managing Anemia!
Cresp the world's firts biosimilar darbepoetin alfa,others improved, conveient, and affordable treatment for anemiaDarbepoetin Alfa: Convenient Solution For Managing Anemia!
Exploring Darbepoetin Alfa Potential Versus Epoetin Beta
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Exploring Darbepoetin Alfa Potential Versus Epoetin BetaErythropoiesis-stimulating agent should be considered in below set of patients
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Cresp®, the world's first biosimilar darbepoetin alfa, offers improved, convenient, and affordable treatment for anemia
Cresp®, the world's first biosimilar darbepoetin alfa, offers improved, convenient, and affordable treatment for anemia
Cresp®, the world's first biosimilar darbepoetin alfa, offers improved, convenient, and affordable treatment for anemia 1 Maintaining Hb Targets in Elderly CKD Patients *Subjects who received at least one dose of darbepoetin. Empowering Elderly CKDCresp®, the world's first biosimilar darbepoetin alfa, offers improved, convenient, and affordable treatment for anemia
Reliable Effectiveness of Darbepoetin Alfa Throughout Dialysis Treatment
Reliable Effectiveness of Darbepoetin Alfa Throughout Dialysis Treatment
A 12-month, prospective, single-center cross-over study assessed the impact of the time of IV darbepoetin alfa injection during dialysis on Hb level, ESA dosing and other parameters. 1 Reliable Effectiveness of Darbepoetin Alfa Throughout DialysisReliable Effectiveness of Darbepoetin Alfa Throughout Dialysis Treatment
Frequent Use of ESA Triggers Variability in Hemoglobin Levels
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Frequent Use of ESA Triggers Variability in Hemoglobin Levels Is frequent ESA administration safe? Changing From rHuEPO to Darbepoetin Alfa for Renal Anemia Darbepoetin alfa’s dose in adult CKD 3 Estimated Cresp® starting dose based on previousFrequent Use of ESA Triggers Variability in Hemoglobin Levels
Monthly Darbepoetin Alfa: A Preferred Choice Among CKD Patients
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Dosing Darbepoetin Alfa: Impact on Dialysis Patients
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Examining the influence of intravenous darbepoetin alfa injection timing on dialysis-associated parametersDosing Darbepoetin Alfa: Impact on Dialysis Patients
Revolutionizing Pediatric Constipation Care for Long-Term Relief With PEG
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Uncovering the benefits of using PEG compared to lactulose for long-term relief in children with functional constipation. Pave the Way to Pain-Free Defecation With PEG Does Your Laxative of Choice Stand the Test of Time? Opt for Long-Term EfficacyRevolutionizing Pediatric Constipation Care for Long-Term Relief With PEG
Navigating Functional Constipation: A collaboration Between Parents and Pediatricians
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Addressing parental concerns in the management of pediatric functional constipation Parental Concerns Pivotal in Managing Pediatric Constipation Addressing Parental Concerns Boosts Treatment Adherence Managing parent's expectations can improveNavigating Functional Constipation: A collaboration Between Parents and Pediatricians
Dosing Darbepoetin Alfa: Impact on Individuals Undergoing Dialysis
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Merits of Darbepoetin utilization in the elderly CKD patients
Merits of Darbepoetin utilization in the elderly CKD patients
Cresp®, the world's first biosimilar darbepoetin alfa, offers improved, convenient, and affordable treatment for anemia 1 Maintaining Hb Targets in Elderly CKD Patients *Subjects who received at least one dose of darbepoetin. Empowering Elderly CKDMerits of Darbepoetin utilization in the elderly CKD patients
Childhood Constipation Poses Notable Challenges for Children and Their Families
Childhood Constipation Poses Notable Challenges for Children and Their Families
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High Dose, Zero Hassle: Achieve Effortless Disimpaction With PEG
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PEG-based laxatives offer the convenience of using a high dose for disimpaction without the risk of side effects associated with lactulose.High Dose, Zero Hassle: Achieve Effortless Disimpaction With PEG
High Dose, Zero Hassle: Achieve Effortless Disimpaction With PEG
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Childhood Constipation Poses Notable Challenges for Children and Their Families
Childhood Constipation Poses Notable Challenges for Children and Their Families
Childhood Constipation Poses. Notable Challenges for Children and Their Families.Childhood Constipation Poses Notable Challenges for Children and Their Families
Exploring the Merits of Darbepoetin Utilization in the Elderly: A Boon or a Bane
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Dosing Darbepoetin Alfa: Impact on Individuals Undergoing Dialysis
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Dosing darbeportin alfa impact on individuals undergoing analysisDosing Darbepoetin Alfa: Impact on Individuals Undergoing Dialysis
Unleash Swift Relief: PEG's Game-Changing Potential
Darbepoetin Alfa: Convenient Solution For Managing Anemia!
Darbepoetin Alfa: Convenient Solution For Managing Anemia!
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What Sets Polyethylene Glycol Apart in Winning Patient Acceptance
What Sets Polyethylene Glycol Apart in Winning Patient Acceptance
Chronic constipation is a surprisingly prevalent concern with far-reaching consequences.What Sets Polyethylene Glycol Apart in Winning Patient Acceptance
Individualizing Hb targets in dialysis patients with anemia
Individualizing Hb targets in dialysis patients with anemia
A condition characterized by decreased levels of red blood cells, and is a complex health issue.Individualizing Hb targets in dialysis patients with anemia
Review of Evidence of 24-Hour Blood Pressure Regulation by Amlodipine
Review of Evidence of 24-Hour Blood Pressure Regulation by Amlodipine
Hypertension acts as the leading factor contributing to the increasing rates of mortality and disability linked to cardiovascular diseases.Review of Evidence of 24-Hour Blood Pressure Regulation by Amlodipine
Treatment Options for Effective Diabetes Management
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Right treatment options and lifestyle changes, managing Diabetes7 Proven Lifestyle Strategies to Prevent Diabetes for a Healthier Future
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Analgesic onset of FA-acetaminophen in a postoperative dental impaction pain model
Analgesic onset of FA-acetaminophen in a postoperative dental impaction pain model
A recent study has shown that fast-acting acetaminophen (FA-acetaminophen) had a quicker onset of action than both commercial acetaminophen caplets (ES-acetaminophen) and commercial ibuprofen liquid-filled gelatin capsules (LG-Ibuprofen). This study findings were published in the journal, Current Medical Research and Opinion.
Two single-center, randomized, inpatient, placebo-controlled, double-blind design clinical trials were carried out utilizing the postoperative dental impaction pain model. Study 1 included 240 subjects, whereas study 2 had 420 subjects. The individuals involved in this study were between the ages of 17 and 50 and were suffering from moderate to severe pain after undergoing the surgical extraction of a minimum of three impacted third molars. The two studies evaluated four different treatment groups: 1,000 mg of FA-acetaminophen, 400 mg of LG-ibuprofen, 1,000 mg of ES-acetaminophen, and a placebo. The double-stopwatch method was used to determine the times to confirm perceptible pain relief (TCPR) and meaningful pain relief (TMPR). Pain intensity and relief were assessed using a 0-10 numerical rating scale for a duration of 6 hours after administering the drug.
The efficacy results demonstrated that all active treatments were statistically superior to the placebo. Within study 1, TCPR was significantly shorter for FA-acetaminophen in comparison to ES-acetaminophen and LG-ibuprofen. Additionally, FA-acetaminophen 1,000 mg showed a significantly shorter TMPR compared to LG-ibuprofen. In both studies 1 and 2, at the 15-minute mark post-administration of the study drug, PID and PAR scores were higher for FA-acetaminophen than LG-ibuprofen.
It can be concluded that FA-acetaminophen demonstrated a faster onset of action in comparison to both ES-acetaminophen and LG-Ibuprofen.
Analgesic onset of FA-acetaminophen in a postoperative dental impaction pain model
Analgesic onset of FA-acetaminophen in a postoperative dental impaction pain model
A recent study has shown that fast-acting acetaminophen (FA-acetaminophen) had a quicker onset of action than both commercial acetaminophen caplets (ES-acetaminophen) and commercial ibuprofen liquid-filled gelatin capsules (LG-Ibuprofen). This study findings were published in the journal, Current Medical Research and Opinion.
Two single-center, randomized, inpatient, placebo-controlled, double-blind design clinical trials were carried out utilizing the postoperative dental impaction pain model. Study 1 included 240 subjects, whereas study 2 had 420 subjects. The individuals involved in this study were between the ages of 17 and 50 and were suffering from moderate to severe pain after undergoing the surgical extraction of a minimum of three impacted third molars. The two studies evaluated four different treatment groups: 1,000 mg of FA-acetaminophen, 400 mg of LG-ibuprofen, 1,000 mg of ES-acetaminophen, and a placebo. The double-stopwatch method was used to determine the times to confirm perceptible pain relief (TCPR) and meaningful pain relief (TMPR). Pain intensity and relief were assessed using a 0-10 numerical rating scale for a duration of 6 hours after administering the drug.
The efficacy results demonstrated that all active treatments were statistically superior to the placebo. Within study 1, TCPR was significantly shorter for FA-acetaminophen in comparison to ES-acetaminophen and LG-ibuprofen. Additionally, FA-acetaminophen 1,000 mg showed a significantly shorter TMPR compared to LG-ibuprofen. In both studies 1 and 2, at the 15-minute mark post-administration of the study drug, PID and PAR scores were higher for FA-acetaminophen than LG-ibuprofen.
It can be concluded that FA-acetaminophen demonstrated a faster onset of action in comparison to both ES-acetaminophen and LG-Ibuprofen.
B-Gn-F plane proves as the most accurate best mandibular midsagittal plane to segment and identify mandible anatomical landmarks
B-Gn-F plane proves as the most accurate best mandibular midsagittal plane to segment and identify mandible anatomical landmarks
According to a recent study, deep learning can segment and identify mandibular midline landmarks with the help of the best mandibular midsagittal plane (MMSP), which is B-Gn-F. This study was published in the European Journal of Medical Research.
This study included 400 participants who were randomly assigned into a training group (n=360) and a validation group (n=40), along with a test group (n=50) comprising normal individuals. PoseNet identified 27 anatomic landmarks from the mandible images from cone-beam computed tomography (CBCT) using the PointRend deep learning mechanism. For the test group, three-dimensional (3D) coordinates were obtained for five central landmarks and two pairs of side landmarks. Using the template mapping technique, every 35 combinations of 3 midline landmarks were screened. For each of the 35 mirror planes, the asymmetry index (AI) was calculated. The top 4 planes having the smallest AIs were compared through volume difference, similarity index, and distance in order to find the plane with the least errors.
At the end of the study, it was found that in 10 ± 1.5 seconds, the mandible was automatically segmented with a 0.98 Dice similarity coefficient. Among the 27 landmarks, the average localization error was 1.04 ± 0.28 mm. The plane created by B (supramentale), Gn (gnathion), and F (mandibular foramen) should be used by MMSP. The average AI grade observed was 1.6. No significant difference was seen in volume or distance, although the similarity index was significantly different.
From the above results, it can be concluded that deep learning may segment and identify mandibular midline landmarks with the help of the best mandibular midsagittal plane (MMSP), which is B-Gn-F.
B-Gn-F plane proves as the most accurate best mandibular midsagittal plane to segment and identify mandible anatomical landmarks
B-Gn-F plane proves as the most accurate best mandibular midsagittal plane to segment and identify mandible anatomical landmarks
According to a recent study, deep learning can segment and identify mandibular midline landmarks with the help of the best mandibular midsagittal plane (MMSP), which is B-Gn-F. This study was published in the European Journal of Medical Research.
This study included 400 participants who were randomly assigned into a training group (n=360) and a validation group (n=40), along with a test group (n=50) comprising normal individuals. PoseNet identified 27 anatomic landmarks from the mandible images from cone-beam computed tomography (CBCT) using the PointRend deep learning mechanism. For the test group, three-dimensional (3D) coordinates were obtained for five central landmarks and two pairs of side landmarks. Using the template mapping technique, every 35 combinations of 3 midline landmarks were screened. For each of the 35 mirror planes, the asymmetry index (AI) was calculated. The top 4 planes having the smallest AIs were compared through volume difference, similarity index, and distance in order to find the plane with the least errors.
At the end of the study, it was found that in 10 ± 1.5 seconds, the mandible was automatically segmented with a 0.98 Dice similarity coefficient. Among the 27 landmarks, the average localization error was 1.04 ± 0.28 mm. The plane created by B (supramentale), Gn (gnathion), and F (mandibular foramen) should be used by MMSP. The average AI grade observed was 1.6. No significant difference was seen in volume or distance, although the similarity index was significantly different.
From the above results, it can be concluded that deep learning may segment and identify mandibular midline landmarks with the help of the best mandibular midsagittal plane (MMSP), which is B-Gn-F.
Evaluation and comparison of the effectiveness of low-level laser therapy and low-intensity pulsed ultrasound in reducing orthodontic pain
Evaluation and comparison of the effectiveness of low-level laser therapy and low-intensity pulsed ultrasound in reducing orthodontic pain
According to a recent study, low-level laser therapy (LLLT) and low-intensity pulsed ultrasound (LIPUS) effectively reduced separation pain when applied in multiple doses during orthodontic treatment. The results of this study were published in the journal, BMC Oral Health.
150 patients were randomly assigned to three groups in this single-blind, randomized controlled trial: the LLLT group, the LIPUS group, and the control group. The first dose of the laser or ultrasound was applied 5 min from the separators' placement, second dose was given after 24 h, and the last dose was administered on both maxillary and mandibular first molars after 48 h. The patients were exposed to the laser for 20 s, using an 810-nm aluminum-gallium-arsenide (AlGaAs) diode laser on continuous mode. For 20 minutes, 1.6 MHz ultrasonic toothbrush treatment was applied (5 minutes for each first molar). The control group was administered the separator without any other intervention. Pain intensity was assessed at several time intervals during the first four days post the separator’s placement, using a Visual Analog Scale (VAS 100 mm).
It was found after assessing 145 patients that a significant difference in pain perception was observed among the three groups after 5 min. Pain level reached its maximum intensity after 24 h. All the assessment time points showed a statistically significant decrease in pain scores for both the laser and the ultrasound groups when compared to the control group. Moreover, the laser and ultrasound group showed no difference between them in terms of reducing the pain scores.
Hence, it can be concluded that LLLT and the LIPUS may effectively reduce the separation pain experienced during orthodontic treatment after the application of multiple doses, without any difference between them.
Evaluation and comparison of the effectiveness of low-level laser therapy and low-intensity pulsed ultrasound in reducing orthodontic pain
Evaluation and comparison of the effectiveness of low-level laser therapy and low-intensity pulsed ultrasound in reducing orthodontic pain
According to a recent study, low-level laser therapy (LLLT) and low-intensity pulsed ultrasound (LIPUS) effectively reduced separation pain when applied in multiple doses during orthodontic treatment. The results of this study were published in the journal, BMC Oral Health.
150 patients were randomly assigned to three groups in this single-blind, randomized controlled trial: the LLLT group, the LIPUS group, and the control group. The first dose of the laser or ultrasound was applied 5 min from the separators' placement, second dose was given after 24 h, and the last dose was administered on both maxillary and mandibular first molars after 48 h. The patients were exposed to the laser for 20 s, using an 810-nm aluminum-gallium-arsenide (AlGaAs) diode laser on continuous mode. For 20 minutes, 1.6 MHz ultrasonic toothbrush treatment was applied (5 minutes for each first molar). The control group was administered the separator without any other intervention. Pain intensity was assessed at several time intervals during the first four days post the separator’s placement, using a Visual Analog Scale (VAS 100 mm).
It was found after assessing 145 patients that a significant difference in pain perception was observed among the three groups after 5 min. Pain level reached its maximum intensity after 24 h. All the assessment time points showed a statistically significant decrease in pain scores for both the laser and the ultrasound groups when compared to the control group. Moreover, the laser and ultrasound group showed no difference between them in terms of reducing the pain scores.
Hence, it can be concluded that LLLT and the LIPUS may effectively reduce the separation pain experienced during orthodontic treatment after the application of multiple doses, without any difference between them.
Impact of silver diamine fluoride and nano silver fluoride on the oral health-related quality of life of children
Impact of silver diamine fluoride and nano silver fluoride on the oral health-related quality of life of children
According to a recent study, Silver diamine fluoride (SDF) and Nano Silver Fluoride (NSF) after 6 months exhibited significant enhancements in children's Oral Health-Related Quality of Life (OHRQoL). It was observed that NSF had a significantly superior impact on OHRQoL compared to SDF. This study’s results were published in the Journal of dentistry.
This study involved 360 children under the age of 4, each having at least one active lesion with an International Caries Detection and Assessment System (ICDAS) score of ≥3. They were randomly divided into two groups: one receiving NSF at the beginning, and the other receiving SDF at the start and after 6 months. The Oral Health-Related Quality of Life (OHRQoL) was assessed using the Arabic version of the Early Childhood Oral Health Impact Scale (A-ECOHIS). Additionally, group comparisons were made using the chi-square test, and the impact of the intervention on OHRQoL was analyzed through multiple linear regression.
In the bivariate analysis and regression analysis (B= -5.02) with confounder adjustments, it was observed that NSF exhibited significantly lower A-ECOHIS scores compared to SDF after a period of 6 months. Both groups showed significant decreases in the A-ECOHIS domain and total scores, except for the social interaction domain in the SDF group.
The above study demonstrated that after a 6-month period, both NSF and SDF led to a significant improvement in children's OHRQoL. However, NSF had a notably greater impact on OHRQoL compared to SDF.
Impact of silver diamine fluoride and nano silver fluoride on the oral health-related quality of life of children
Impact of silver diamine fluoride and nano silver fluoride on the oral health-related quality of life of children
According to a recent study, Silver diamine fluoride (SDF) and Nano Silver Fluoride (NSF) after 6 months exhibited significant enhancements in children's Oral Health-Related Quality of Life (OHRQoL). It was observed that NSF had a significantly superior impact on OHRQoL compared to SDF. This study’s results were published in the Journal of dentistry.
This study involved 360 children under the age of 4, each having at least one active lesion with an International Caries Detection and Assessment System (ICDAS) score of ≥3. They were randomly divided into two groups: one receiving NSF at the beginning, and the other receiving SDF at the start and after 6 months. The Oral Health-Related Quality of Life (OHRQoL) was assessed using the Arabic version of the Early Childhood Oral Health Impact Scale (A-ECOHIS). Additionally, group comparisons were made using the chi-square test, and the impact of the intervention on OHRQoL was analyzed through multiple linear regression.
In the bivariate analysis and regression analysis (B= -5.02) with confounder adjustments, it was observed that NSF exhibited significantly lower A-ECOHIS scores compared to SDF after a period of 6 months. Both groups showed significant decreases in the A-ECOHIS domain and total scores, except for the social interaction domain in the SDF group.
The above study demonstrated that after a 6-month period, both NSF and SDF led to a significant improvement in children's OHRQoL. However, NSF had a notably greater impact on OHRQoL compared to SDF.
The efficacy and safety of a toothpaste containing bioactive glass-ceramic in treating dentinal hypersensitivity
The efficacy and safety of a toothpaste containing bioactive glass-ceramic in treating dentinal hypersensitivity
According to a recent study, the bioactive glass-ceramic (HX-BGC) and NovaMin toothpaste exhibited more significant effects in addressing dentinal hypersensitivity when compared to the negative control group. No adverse reactions associated with the experimental toothpastes were noted. This study’s research findings were published in the Journal of Dentistry.
In this single-center, randomized, double-blind study, participants were randomly allocated to use one of the HX-BGC, NovaMin, or negative control toothpastes. Follow-up examinations were conducted immediately after a single use and at 2 weeks, 4 weeks , and 6 weeks. Schiff and Yeaple indices were used for intra-group and inter-group comparisons. The safety of the experimental toothpastes was evaluated through participant feedback and oral soft tissue examinations.
There was an increase in Yeaple indices across all groups, with significant differences noted between the HX-BGC group and the other two groups after a continuous 2-week period of use. Schiff indices decreased in all groups, with the NovaMin group demonstrating significant differences when compared to the negative control group. Significant improvement was observed in both the HX-BGC group and the NovaMin group by weeks 4 and 6 compared to the negative control group in both indices. The HX-BGC group exhibited better results in the Yeaple index compared to the NovaMin group. Additionally, no serious adverse reactions related to the toothpastes were reported or observed among the participants.
The above study confirmed the efficacy of HX-BGC in treating dentinal hypersensitivity and supported the clinical use of dentifrices formulated with HX-BGC. Both the HX-BGC and NovaMin toothpaste groups exhibited significantly greater efficacy in managing dentinal hypersensitivity compared to the negative control group. There were no adverse reactions reported in relation to the experimental toothpastes.
The efficacy and safety of a toothpaste containing bioactive glass-ceramic in treating dentinal hypersensitivity
The efficacy and safety of a toothpaste containing bioactive glass-ceramic in treating dentinal hypersensitivity
According to a recent study, the bioactive glass-ceramic (HX-BGC) and NovaMin toothpaste exhibited more significant effects in addressing dentinal hypersensitivity when compared to the negative control group. No adverse reactions associated with the experimental toothpastes were noted. This study’s research findings were published in the Journal of Dentistry.
In this single-center, randomized, double-blind study, participants were randomly allocated to use one of the HX-BGC, NovaMin, or negative control toothpastes. Follow-up examinations were conducted immediately after a single use and at 2 weeks, 4 weeks , and 6 weeks. Schiff and Yeaple indices were used for intra-group and inter-group comparisons. The safety of the experimental toothpastes was evaluated through participant feedback and oral soft tissue examinations.
There was an increase in Yeaple indices across all groups, with significant differences noted between the HX-BGC group and the other two groups after a continuous 2-week period of use. Schiff indices decreased in all groups, with the NovaMin group demonstrating significant differences when compared to the negative control group. Significant improvement was observed in both the HX-BGC group and the NovaMin group by weeks 4 and 6 compared to the negative control group in both indices. The HX-BGC group exhibited better results in the Yeaple index compared to the NovaMin group. Additionally, no serious adverse reactions related to the toothpastes were reported or observed among the participants.
The above study confirmed the efficacy of HX-BGC in treating dentinal hypersensitivity and supported the clinical use of dentifrices formulated with HX-BGC. Both the HX-BGC and NovaMin toothpaste groups exhibited significantly greater efficacy in managing dentinal hypersensitivity compared to the negative control group. There were no adverse reactions reported in relation to the experimental toothpastes.
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