Fecal accumulation in the rectum can cause distension and subsequent soiling, MuOUT, pathophysiological cause, pediatric functional
Stool withholding behavior is the primary pathophysiological cause of pediatric functional constipation. Stool retention can potentially lead to the development of a megarectum, which in turn can result in reduced defecation sensation and fecal soiling (Figure 1).2
According to pathophysiological studies, withholding behavior is reported in 37%–91% of children with functional constipation, palpable fecal mass on abdominal examination in 33%–68%, and fecal soiling in 33%–77%.2
Passing soft stools without any straining is a crucial aspect in the management of pediatric functional constipation.2 Laxatives are commonly preferred for the treatment of pediatric functional constipation.2,3
A randomized single-blinded clinical trial study by Bastaoros et al revealed that treatment with PEG results in significant improvement in excessive stool retention compared to lactulose.3
Abbreviations ▼
PEG: Polyethylene glycol.
References ▼
1. Pashankar DS, Loening-Baucke V, Bishop WP. Safety of polyethylene glycol 3350 for the treatment of chronic constipation in children. Arch Pediatr Adolesc Med. 2003;157(7):661–664. 2. Tran DL, Sintusek P. Functional constipation in children: What physicians should know. World J Gastroenterol. 2023;29(8):1261–1288. 3. Bastaoros O, Gad MA, Eskander AE, et al. The use of polyethylene glycol as a maintenance treatment of functional constipation in children living in Egypt. Egyptian Pediatr Assoc Gazette. 2023;71:67.
LMRC Code: GGI-CO-A1-AQS-300024228-ELC-H24-0882
For the use of a Registered Medical Practitioner, Hospital or Laboratory only.
Disclaimer:
The images are for illustrative representation only and do not depict actual medical products, procedures, or outcomes. Refer to official medical guidance and product information for accurate details.
All content including: text, images, audio, or other formats were created for medical educational purposes only. Offerings for continuing education are clearly identified and the appropriate target audience is identified. This communication is restricted for the use of HCPs and must not be shared in public domain. The opinions expressed in this video are solely the views of the speaker. The presentation may contain off label usage of drug(s) aimed at educational purpose only. Dr. Reddy’s Laboratories Ltd including but not limited its Affiliates strictly does not recommend any off label usage of its marketing products. Prior to treatment kindly refer to the latest prescribing information approved by the local authorities. No part of this content may be used, reproduced, transmitted or stored in any form without the written permission of Dr. Reddy’s.
