Rickettsial infections
Where to use
Treat or prevent infections that are proven or strongly suspected to be caused by bacteria. DOXT SL is a tetracycline-class antimicrobial indicated for:
Specific bacterial infections
Alternative treatment for selected infections when penicillin is contraindicated
Sexually transmitted infections
Ophthalmic infections
Adjunctive therapy in acute intestinal amebiasis and severe acne
Respiratory tract infections
Anthrax, including inhalational anthrax (post-exposure)
Prophylaxis of malaria
How to use
Adults:
The usual dose of oral Doxycycline is 200 mg on the first day of treatment (administered 100 mg every 12 hours) followed by a maintenance dose of 100 mg/day. In the management of more severe infections (particularly chronic infections of the urinary tract), 100 mg every 12 hours is recommended. (2.1)
For children above eight years of age:
The recommended dosage schedule for children weighing 100 pounds or less is 2 mg/lb of body weight divided into two doses on the first day of treatment, followed by 1 mg/lb of body weight given as a single daily dose or divided into two doses on subsequent days. For more severe infections up to 2 mg/lb of body weight may be used. For children over 100 lbs, the usual adult dose should be used. (2.2)
What are the side effects?
Anorexia
Rash
Nausea
Photosensitivity
Vomiting
Urticaria
Diarrhea
Hemolytic anemia
Safety advises
Doxycycline is contraindicated in people who have shown hypersensitivity to any of the tetracyclines.
The use of drugs of the tetracycline-class during tooth development (last half of pregnancy, infancy, and childhood to the age of 8 years) may cause permanent discoloration of the teeth (yellow-gray-brown).
Clostridium difficile-associated diarrhea: Evaluate patients if diarrhea occurs.
Photosensitivity manifested by an exaggerated sunburn reaction has been observed in some individuals taking tetracyclines. Limit sun exposure.
Overgrowth of non-susceptible organisms, including fungi, may occur. Re-evaluate therapy if superinfection occurs.